New Principles of Immunology: All 27 veterinary schools in North America are in the process of changing their protocols for vaccinating dogs, based on current research leading to the development of new principles of immunology. A dog's immune system matures fully by age 6 months. If a modified live virus vaccine is given after 6 months of age, it produces immunity which should be good for the life of the dog. If another modified live virus vaccine is given a year later, the antibodies from the first vaccine neutralize the antigens of the second vaccine and there is little or no effect. Annual boosters for Parvo and Distemper are now considered unnecessary and subject the dog to potential risks of allergic reactions and such diseases as immune-mediated hemolytic anemia. There is no scientific documentation to back up label claims for annual administration of modified live virus vaccines. Puppies receive antibodies through their mother's milk. This natural protection can last 8 to 14 weeks. Puppies should NOT be vaccinated at younger than 9 weeks, because maternal immunity will neutralize the vaccine and little protection (0 - 38%) will be produced. Vaccination at 6 weeks will, however, DELAY the timing of the first highly effective vaccine. Vaccinations given 2 weeks apart actually SUPPRESS, rather than stimulate, the immune system. Vaccinations should be given beginning at 9 weeks of age (or later if the pup is till nursing), then every 3 to 4 weeks apart up to about 16 weeks of age. Another vaccination given sometime after 6 months of age (usually at 16 months) should provide lifetime immunity. Remember that an educated and informed decision needs to be made when considering the risks versus the benefits of vaccinating your pets. Note: Rabies vaccines must be given according to State Law. IMPS also has all dogs Heartworm tested prior to adoption.